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夏红娣丧夫后独抚儿子聂伟，反被儿媳赶出家门。途中救起失忆的吴廷正，二人相依为命。五年后，他们摆摊遭嫉，吴廷正护夏红娣受伤恢复记忆，却得知自己患肾衰。夏红娣愿捐肾，吴廷正感动，誓要给她幸福生活。。FRAMING AGNES turns the talk show format inside out in response to media's ongoing fascination with trans people. The film breathes life into six previously unknown stories from the archives of the UCLA Gender Clinic in the 1950s.。